Inflammation I

Module code

mlsInflammationI-01a

Abbreviated title

Inflammation I

Module components

Lecture, seminar, practical exercise

When

Semester 2

Module coordinator/

Organiser

R. Häsler

Dermatology

Lecturers

R. Häsler (Dermatology), P. Rosenstiel (IKMB); C. Stürner (Neurology), J. Baines (IEM), S. Sebens (IET) and colleagues

Contact hours

Lecture 2 CH           Seminar 2 CH              Diagnostics practical exercise 2 CH

Workload

Total: 150 h

Lecture: 30 h
Attendance time 26 h, revision 4 h
Seminar: 60 h
Attendance time 28 h, preparation 22 h, revision 10 h
Practical exercise: 60 h
Attendance time 38 h, preparation 12 h, revision 10 h

Credit points

5 (lectures 1 CP, seminar 2 CP, practical exercise 2 CP)

Requirements

MolBio passed

Expected outcome

Knowledge: Students

- have a basic understanding of pathophysiological processes, especially of interactions between genetic and environmental factors leading to inflammatory diseases in barrier organs

- are familiar with important inflammatory diseases, their basic diagnostics and therapies

- can name the main symptoms of those diseases

- can define the most important patho-biochemical connections.

Skills: Students

- can apply statistical tests and bioinformatics software for data evaluation.

Competences: Students

- are able to familiarize themselves with a scientific topic through literature research

- understand scientific publications and can discuss them

- can develop an oral presentation on the basis of scientific publications and present it

- are aware of the social and ethical implications of disease research and take them into account in their research work.

Content

Lecture: Pathogenesis of chronic inflammatory diseases [e.g. acute/chronic, mononuclear inflammatory responses; autoimmune/infection-caused inflammatory responses; asthma, sarcoidosis, psoriasis, IBD, arteriosclerosis, coronary heart diseases, inflammatory diseases of the CNS]

Seminar: Discussion of publications on chronic inflammatory disease manifestations discussed in the lecture

Practical exercise: Rotation through diagnostic labs (e.g. osteology, staining/microscopy, bacterial cell cultures) executing lab experiments under supervision

Module evaluation/

exam

Graded

Written exam

Media used

PPT presentations, scientific publications.

Literature

Cavaillon J-M, Singer M, Inflammation: From Molecular and Cellular Mechanisms to the Clinic (Wiley 2017)

Bondy, S C; Campbell A, Inflammation, Aging, and Oxidative Stress (Humana Press 2016)

Miyasaka M, Takatsu K, Chronic Inflammation – Mechanisms and Regulation (Springer 2016)