Oncology II 2023

Focus area Oncology II

Module code


Abbreviated title

Oncology II

Module components

Lab seminar, lab practical, joint seminar of all focus areas


Semester 3

Module coordinator/


S. Sebens



N. Arnold (Gynaecology), L. Lenk (Pediatrics), A. Trauzold (General and thoracic Surgery), S. Sebens (IET); M. Peipp, T. Valerius (Med. Department II); principal investigators of research groups working on research topics of focus areas (joint seminars)

Contact hours

Practical 9 CH               Lab seminar 1 CH            Joint seminar 1 CH






Total:  330 h

Lab practical: 240 h
Attendance time 100 h, preparation 60 h, revision 80 h

Lab seminar: 60 h

Attendance time 14 h, preparation 26 h, revision 20 h
Joint seminar “Current affairs”:
Attendance time 14 h, preparation 10 h, revision 6 h

Credit points

11 (practical 8 CP, lab seminar 2 CP, joint seminar 1 CP)


Oncology I passed

Expected outcome

Knowledge: Students

- have an in-depth understanding of physiological and molecular/cell biological processes which influence malignant diseases

- understand lab techniques for oncological research described in the literature and can explain essential methods

- have in-depth knowledge of the experiments conducted during the practical.

Skills: Students

- can conduct the different steps of their lab experiments and explain them

- are able to perform quality control measures for the results obtained

- can analyse the results and put them into relation to the research area.

Competences: Students

- can plan experiments, analyse the data and interpret results gained

- can reflect their own work critically and integrate new results adequately

- can familiarize themselves with a new topic and develop research approaches

- are aware of the connections between the topics of the different focus areas, can link and explain them.



Seminar: Planning and preparation of a project in the seminar by literature research and discussions with fellow students and lecturers.

Discussion of method papers: sequencing techniques, immunohistochemistry, fluorescence in –situ hybridisation; comparative genome hybridisation on arrays; blotting techniques.

Practical: Performance of experiments for a lab project on topics such as effect of oncogenes, tumour supressor genes, development of mutations; signal transduction in cells and analysis of results. Preparation of tumour cells (RNA/DNA/proteins) for their application in various lab techniques.

Joint seminar: Joint discussion of papers relevant for all focus areas.

Module evaluation/



Scientific project thesis with oral presentation

Media used

PPT presentations, lab instructions, lab experiments.


Pecorino L, Molecular Biology of Cancer Mechanisms, Targets, and Therapeutics (OUP 4th edition, 2016)

Weinberg RA, The biology of Cancer (Garland Publishing 2nd revised edition, 2013)

Current original publications and reviews